Friday, 30 January 2015

Protein synthesis



The first and foremost process to occur in protein synthesis is transcription. Transcribing begins with an enzyme called RNA polymerase which aids in the unwinding of DNA. Instantly the enzyme will break the hydrogen bonds which originally held the DNA together.  Subsequently RNA will form from RNA nucleotides which can be found anywhere floating in the nucleus. To construct a proper MRNA complementary base paring between the DNA and MRNA is essential. Without proper base pairing the necessary protein cannot be made. This holds true for more aspects than just transcription.  The bases are nitrogenous. And on a DNA strand cytosine and guanine are paired as well as adenine and thymine re paired. RNA slightly differs as thymine does not exist and is replaced with uracil. Once the single strand of MRNA is complete it easily leaves the nucleus finding its way out to the ribosomes which could either be free floating in the cytoplasm or in the endoplasmic reticulum. Leaving the nucleus and traveling into a ribosome directs us into the second stage, translation. During translation TRNA carry amino acids to the ribosome where they can be dropped off at the MRNA, planting themselves  at the correct complementary base pair. At this time only two TRNA s are aloud at a time. The TRNA in the front will drop of its Amino acid and leave, searching for another amino acid where the one in behind will take its place. This process occurs until a stop codon has been read. Amino acids will keep on collecting themselves to make a polypeptide until it’s a complete protein. 

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